How to design a clinical trial—equipoise, bias, and big data
BY DR MICHAEL FEHLINGS

References and additional resources:
- A podcast with Michael Fehlings discussing his personal tips for securing research funding was published as part of a special Research Top Tips series, from Myelopathy Matters (Myelopathy.org) and AO Spine RECODE-DCM. The initiatives worked together to accelerate knowledge discovery that can change outcomes in Degenerative Cervical Myelopathy (DCM). Each episode takes a dive into a fundamental concept of scientific research, with leading spine researchers talking us through their recipes for success in their own words.
- The AO Program for Education and Excellence in Research (AO PEER) is a collection of clinical research resources, reference documents, and learning opportunities for anyone wanting to learn more about doing research. The Grant Writing and Study Protocol module of AO PEER includes useful templates for applying for grants.
- Badhiwala JH, Wilson JR, Witiw CD, et al. The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data. Lancet Neurol. 2021 Feb;20(2):117-126.
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